[동물용 DXA] DXA 방식을 적용한 동물용 골밀도 및 체성분 검사, InAlyzer
Ultra high resolution digital radiography system with DXA Body Composition analysis function.
Dual energy X-ray Absorptiometry (DXA) technology.
A small x-ray source exposes the entire animal to a fan shaped beam of both high and low energy x-rays.
A high-resolution digital picture (108x108um) is taken by using CCD detecter with TDI (time delayed Integration) method.
The ratio of attenuation of the high and low energies allows the InAlyzer to separate bone from tissue and, from within the tissue samples, the lean and fat.
DXA (Dual energy X-ray Absorptiometry)
Body Composition Analysis function
Academic and pharmaceutical researchers commonly use mice and small animals for investigations of genetics, cellular physiology, and of agents affecting bone or soft-tissue composition.
Bone and tissue composition measurement using dual energy x-ray absorptiometry (DXA) measurement eliminate the need for destructive chemical analysis, a time and labor-consuming process that requires days or weeks to complete.
DXA measurement allows the researcher the opportunity to make multiple measurements in situ during the life of the animal – providing true longitudinal measures.
Unfortunately, the spatial resolution of table DXA measurement is too poor for mice and the rectilinear scanning process of older peripheral DXA measurement require as much as five minutes for a total body acquisition with relatively poor precision and spatial resolution.
30 Seconds!!
The long process requires careful sedation techniques and often endangers animal safety. Providing bone mineral and body composition results from total body imaging in less than 30 seconds.
Fast imaging allows faster access to important data and is safer on animals.
Ultra high resolution
Digital Radiography System
Ultra-high resolution x-ray imaging is an important tool in investigating a variety of disease states. From metastatic cancer to arthritis and osteoporosis, small animal testing models are commonly used.
Both in vivo and ex vivo planar imaging is used to screen, track, and evaluate structural changes in these studies.
Dual energy x-ray absorptiometry (DXA) systems allow researchers to take images directly in the vivarium to protect the integrity of the colony.
These planar imaging systems are less expensive, subject animals to lower doses, and provide faster results than microCT systems.
Meet the powerful digital-imaging solutions specially designed for veterinary practices.
Image software, combined with the InAlyzer DR System, allows you to transform your veterinary practice to digital, easily and affordably.
These systems are optimized with precisely the features your veterinary practice needs – including vet-specific order entry and exam views, customized animal-image processing and a full suite of veterinary measurement tools.
Really acquire fat, lean, and bone data from the total body composition data in vivo
Basically allows automated, accurate and precise measurement of bone and tissue for small animals weighing 10-500g (e.g., mice, lemmings, rat) including middle animals weighting 500g-3000g.
Using a lower x-ray energy than that used for peripheral densitometry in humans in order to achieve contrast in the low density bone.
Excellent precision of BMD and Fat makes InAlyzer ideal for longitudinal studies.
With an image area of 210mm x 315mm (bigger window, optional), the InAlyzer can image the entire body of most mice including hamsters and Mongolian gerbils, as well as rabbits and guinea pigs.
The standard total body result focuses on the sub-cranial region improving sensitivity by excluding the inactive bone and tissue of the cranium.
There are manual regions of interest (ROIs) for selected areas within the total body image, such as spine and femur.
Researchers using the middle animal can image large portions of the animal and position ROIs over their area of interest (i.e. entire leg, spine, abdomen) producing both bone and tissue results.
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